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what's new

• The 2007 Pipeline Report
  Experimental Treatments and Preventive Therapies for HIV, Hepatitis C, and Tuberculosis • July 2007
  The Pipeline Report is the Treatment Action Group’s annual review of experimental technologies that have the potential to solve critical unmet medical needs surrounding HIV infection and AIDS. (added 7/20/2007)
• Treatment Action Group Supports Maraviroc Approval
• Ensayos clinicos – slide presentation en español
  (requires powerpoint plugin to view)

current reports

• The 2007 Pipeline Report
  Experimental Treatments and Preventive Therapies for HIV, Hepatitis C, and Tuberculosis • July 2007
• Who's got the POWER? TAG position paper on darunavir/r approval
  examining data and drug interactions on TMC114/r brand name Prezista^®, a ritonavir (r) -boosted protease inhibitor
• AIDS Activism, Boehringer Ingelheim, and the Broken Social Contract
  Remarks by Mark Harrington at BI Symposium "HIV: From Yesterday to Tomorrow"
• CROI Report 2006
  13th Conference on Retroviruses and Opportunistic Infections Denver, CO
• Antiretrovirals in the Pipeline July 05
  chapter from full report, also in separate pdf format
• Lactic acidosis
  a side-effect of the long term use of the reverse transcriptase inhibitor (RTI) class of HIV drugs (added 9/19/2005)
• TAG supports approval of Aptivus™ brand tipranavir
  Position paper on accelerated FDA approval for novel protease inhibitor tipranavir

  Zero Tolerance (added 3/16/2005)
  2005 Pipeline Report—part I Complications

  Epzicom brand abacavir/lamivudine QD: the difference between drugs and new drugs

  Two out of three ain't bad: Truvada enters the market at full blast

  PEPFAR and expedited antiretroviral review
  HHS announced an expedited FDA review process for antiretroviral fixed dose combination (FDC) products

  NIH: Open the Doors
  NIH Hearing on Norvir 400% price increase

  Breaking barriers or breaking the bank?
  Position paper on Fuzeon brand enfuvirtide (T-20)

  CROI 2004 Pipeline Report

  WHO Guidelines for Antiretroviral Therapy
  Scaling up antiretroviral therapy in resource limited-settings 2003 Revision

  Position paper on 908 (fosamprenavir)

  Position paper on FTC (emtricitabine) brand name Emtriva approval

  ICAAC Roundup (posted 3/14/2005)
  Report from the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) is the annual meeting of the American Society for Microbiology.

2003

• Retrovirus 2003 Conference – Antivirals Pipeline Report - References
• Position Paper on Atazanavir (BMS-232623), brand name Reyataz®
• Report from the 3rd International STI Workshop
  Montréal, Quebec, Canada - March 23-24 2002. Sponsored by: Foundation for AIDS & Immune Research, The Forum for Collaborative HIV Research, Gay Men's Health Crisis, Project Inform, Treatment Action Group
• Coming, Going and Gone: The Drug Development Pipeline, 2002
• Ten Texts on Saquinavir: Its Rapid Rise & Fall
  A saga of drug the development process. Current and earlier texts about saquinavir (Invirase), activists against, pharmaceutical and FDA for.
• STI 2000 (pdf format only)
  Structured Treatment Interruptions Workshop October 13-15, 2000 Newton, MA. Summary of current and proposed research protocols.
• Therapeutic Drug Monitoring (TDM): Ready for Prime Time? by Mark Harrington
• Survey of Structured Treatment Interruptions Reports
• Structured Treatment Interruptions Workshop Report

Resource Links

• 2003 WHO ART Guidelines
  Scaling Up Antiretroviral Therapy in Resource Limited Settings: Treatment Guidelines for a Public Health Approach 2003 Revision

Archived Reports

• New HIV Treatment Guidelines Could Revolutionize HIV Care for People with AIDS (6/19/97)
• Saquinavir Scam (6/11/97)
• Current Treatment Strategies: 14 Points to Consider (2/25/97)
• NIH Panel to Define Principles of Therapy of HIV Infection, Department of the Interior Auditorium, 13-14 November 1996. zipped Word version | zipped text version
• Problems with Protease Inhibitor Development Plans
  Written for the National Task Force on AIDS Drug Development, February 23, 1995, Washington, D.C. Discusses development and research of protease inhibitors with recommendations for future clinical trial design. zipped Word-formatted version for downloading | zipped text version for downloading

  The Challenge Ahead by Gregg Gonzalves

  36 basic scientists working in AIDS interviewed during April and May 1993 discuss scientific issues, practical problems, and outline practical means of remedying the situation. zipped Word version for downloading

  The Crisis in AIDS Research by Mark Harrington

  An overview of AIDS research, written in 1993, with suggestions for changes in fundamental approaches to how the virus, treatments, and research goals are viewed. zipped Word version for downloading

  AIDS Research at the NIH: A Critical Review by Gregg Gonsalves and Mark Harrington

  Part I: Summary. Part II: The NIH, A User's Guide. VIII International Conference on AIDS, Amsterdam, the Netherlands, July 20, 1992. zipped Word versions for downloading: Part I | Part II

Each of these papers is available in hard copy format by writing or calling TAG at the address and numbers below. Please note that all papers provided here are dated. While the information contained in them is important, treatment options have changed since the dates of their writing.

TAG papers are provided here in zipped text-only format for downloading and reading with a text editor. If you don't have an unzip application, you can download shareware called pkunzip for DOS, WinZip for Windows, or Zipit for Macs. Extract the zipped program onto your harddrive and associate the zip extension with the application both in your browser and on your harddrive. Then when you click on a zipped file to download, your harddrive will automatically unzip the file and you'll be able to read it with whatever text reader or word processing application you use.