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| TAG’s Michael Palm Basic Science, Vaccines & Prevention Project works to strengthen basic science, immunology, and biomedical HIV prevention research efforts directed at clarifying understanding of how HIV destroys the immune system, how to develop effective immune-based therapy strategies, and how to develop biomedical preventive approaches such as vaccines, microbicides, and treatments to prevent HIV infection pre- and post-exposure. For more information, see “Michael Palm Project Grant Awarded.” |  |
Michael Palm Basic Science, Vaccines & Prevention Project Weblog
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The Michael Palm Basic Science, Vaccine & Prevention Project is conducting an ongoing series of interviews with scientists whose work focuses on issues relating to the immunology, pathogenesis and biomedical prevention of HIV infection.
- Interview with Steven Deeks of UCSF (posted 11/30/2007)
- Discussing the pathogenesis of drug resistance, focusing on virus host interactions and how reductions in viral fitness can lead to improved immunologic outcomes.
- Interview with Douglas Nixon
- Discussing the pathogenesis of drug resistance, focusing on virus host interactions and how reductions in viral fitness can lead to improved immunologic outcomes.
Current Project Articles
- TAG Updates on the Merck HIV Vaccine Trial (STEP/HVTN 502)
Information, links and commentary regarding the results of the Merck HIV vaccine trial presented on November 7 in Seattle. - Notes from the NIAID Workshop on Immune Activation and HIV Pathogenesis
- The PD-1 Palaver
Does a new molecule labeled "program death-1" (PD-1) play a role in shutting down virus-specific T cell responses? - Gut Reactions
a renewed interest in studying the potential impact of HIV infection on CD4 T cells in the gut in the hopes of answering outstanding questions about HIV pathogenesis. - Immune Based Therapies & Preventive Technologies Pipeline Tables
Preventive Vaccines • Microbicides • Pre-Exposure Prophylaxis (PrEP) • Therapeutic Vaccines • Cytokine & Immunomodulators • Gene Therapies - SMART Stops Stopping
Article on the termination of the Strategies for the Management of AntiRetoviral Therapy treatment interruption trial. - Co-Receptor Conundrum
The complex biology of chemokine receptors, a new target for HIV therapeutics. - Research on Pre-Exposure Prophylaxis (PrEP)
On April 25, 2006 TAG co-sponsored a community forum about Research on Pre-Exposure Prophylaxis (PrEP) with CHAMP and GMHC. Background information and Powerpoint presentations are available on CHAMP’s website. - That was the Year That Was: 2005 Year in Review
News updates from TAG's Michael Palm Basic Science, Prevention, and Vaccines Project are published on an ongoing basis on the Project weblog (added 02/07/2006) - Treatment Action Group Statement on the Termination of the SMART Study
- Cure Story Circulates
Story from "News of the World," a UK tabloid, added to Basic Science blog. Review and commentary. - TAG's Basic Science & Vaccine Project Weblog
Introducing TAG's Basic Science Project blog with highlighted articles and abstracts from September's science journal publications. Comments are welcome. - Immune-Based Therapies and Preventive Technologies Pipeline
Chapter in pdf format
for downloading • full report also available.
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