ADAP drugs: ofloxacin

ofloxacin (Floxin)

Drug description

Ofloxacin is an anti-infective drug used for the treatment of lower respiratory infections, skin infection, and urinary tract infections including prostatitis, gonorrhea, cervicitis and urethritis. Ofloxacin has broad activity against bacterial infections and is used in combination with other drugs to treat tuberculosis.

Side effects
Common side effects include restlessness, nausea, diarrhea, vomiting and abdominal pain. Less common are unpleasant taste, decreased appetite, dry mouth, rash, tremors, confusion, sleep disorders, nervousness, drowsiness, hallucinations, dizziness, and photophobia, which is a strong reaction to bright light. Seizures can be fatal if not treated promptly.

Dosage
Administration with antacids, iron salts, sucralfate, or zinc salts decreases absorption. Ofloxacin is given in pill form, 200-400 mg every 12 hours on an empty stomach at least 1 hour before or 2 hours after meals with a full glass of water. Do not take with food.

How long it may take to work
Symptoms should improve within a few days. Length of time for complete resolution depends on the type and site of infection.

Managing side effects
Drink at least 2 quarts of high calorie fluids such as juices and nectars per day to prevent crystal formation in the urine. Antacids or iron should not be taken within 2 hours of ofloxacin. Avoid driving or other activities requiring alertness. Wear sunglasses and avoid prolonged exposure to bright light to prevent photophobia. Rinse your mouth frequently, practice good oral hygiene and use sugarless gum or candy to reduce symptoms of dry mouth.

This information is specific to the use of this medication for HIV-related conditions. For additional information about this drug for other conditions, refer to: www.nursespdr.com/ and www.healthanswers.com/Library/library_fset.asp

The drug descriptions on these pages are intended for informational purposes only. The Network does not promote or endorse the use of any specific treatment for any health-related condition. The medications described here can only be dispensed by a licensed health care professional. The information may have changed since these pages were updated, though every effort is made to keep these pages current. Please contact The Network at (800) 734-7104 to make sure you have the most up-to-date information

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