ADAP drugs: nystatin

nystatin
(Mycostatin, Mykinac, Nilstat, Nystex, O-V Statin)

Drug description

Nystatin is a common topical treatment for thrush. Thrush can show up in the mouth, on the tongue or the gums. Thrush can also appear on the skin. It is difficult to determine whether thrush has spread throughout the body, but white patches or red blotches in the mouth are common signs, as well as a change in the taste of food. Thrush can cause a sore throat, pain when swallowing, and even nausea. Oral nystatin is also used for treatment of intestinal candidiasis or to prepare the bowel for GI surgery.

Side effects
Nystatin can temporarily affect the sense of taste and thus decrease appetite. Some products may contain propylene glycol, alcohol, parabens, or benzyl alcohol. Avoid use if you are sensitive to these additives. Other side effects can be nausea, vomiting, diarrhea, and stomach pain.

Dosage
Use regularly several times a day. The drug will be effective only if you follow directions carefully. Nystatin comes in tablets or a liquid suspension that is meant to be swished for several minutes around in the mouth and then swallowed. For vaginal infections, insert one vaginal tablet daily and lie down for at least 30 minutes following administration. Vaginal treatment should be continued during menstruation. Avoid use of tampons during therapy.

How long it may take to work
Symptomatic relief usually occurs within 24-72 hours after starting therapy. Therapy for a period of 2 weeks is usually sufficient but more prolonged therapy may be necessary. Therapy should be continued for 48 hours after symptoms have disappeared to prevent relapse.

Managing side effects
During treatment for vaginal candidiasis, use sanitary napkins to prevent staining of clothing or bedding. Refrain from sexual contact during therapy or have partner wear a condom to prevent reinfection. When taking oral doses, it is best taken on an empty stomach to avoid nausea, vomiting, and GI distress.

This information is specific to the use of this medication for HIV-related conditions. For additional information about this drug for other conditions, refer to: www.nursespdr.com/ and www.healthanswers.com/Library/library_fset.asp

The drug descriptions on these pages are intended for informational purposes only. The Network does not promote or endorse the use of any specific treatment for any health-related condition. The medications described here can only be dispensed by a licensed health care professional. The information may have changed since these pages were updated, though every effort is made to keep these pages current. Please contact The Network at (800) 734-7104 to make sure you have the most up-to-date information

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